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Fontainea picrosperma, commonly called the blushwood tree, is a jungle tree in the family Euphorbiaceae endemic to Queensland in Australia, where it grows on the Atherton Tablelands. [1]
Summary
An anti-cancer drug referred to as EBC-46 has been established from an extract of the fruits of Fontainea picrosperma. Trials have actually shown that it has activity versus four various types of tumours, consisting of basal-cell cancer, cancer malignancy, squamous cell cancer and breast adenocarcinoma. The fruits are poisonous to humans if eaten. [3]
Stem
Generous watery red exudate appearing rapidly in the blaze.
Leaves
Oil dots noticeable with a lens, practically noticeable to the naked eye. Leaf blades about 7-15 x 2-5 cm. Petioles shallowly funnelled or flattened on the upper surface area, the margins angular or a little winged. Young shoots outfitted in pale yellowish hairs. Twig exudate like that in the blaze.
Flowers
Petals in male flowers about 5-6 mm long and about 7-8 mm long in female flowers. Petals largely white, tomentose. Disk orange. Preconceptions ten, radiating like octopus arms.
Fruit
Fruit about 25 mm long and about 20 mm diam. Endocarp rather thick, stellate in transverse area, often 5-pointed in transverse section.
Seedlings
Cotyledons broadly ovate, about 45-55 x 30-40 mm, 3-veined at the base. At the tenth leaf phase: leaves lanceolate to ovate, peak acuminate, base obtuse, upper surface of leaf blade glabrous; oil dots small, indistinct, noticeable only with a lens. Seed germination time 26 to 58 days.
Distribution and Ecology
Endemic to NEQ, restricted to the Atherton Tableland. Altitudinal range from 700-1100 m. Grows as an understory tree in well developed rain forest.
Natural History and Notes
Fallen fruit consumed by Cassowaries and Musky Rat-kangaroos. [4]
This trees grow only and specifically In the far north-eastern part of Queensland Australia, in the rainforests grows the Blushwood Berry tree referred to as Hylandia Dockrillii.
It grows at high elevations of 400 to 1100 meters in the well-developed rainforest at different locations and reaches heights of up to 25 meters. Blushwood berries are the fruit of the Blushwood tree. The tree’s berries have has extraordinary medical residential or commercial properties and its main part EBC-46 may take concern in repairing the immune system and DNA damaged cells in the future of holistic treatments.
Blushwood Berry
Chemical extracts from the berries of Australian blushwood tree (Hylandia dockrillii) have actually revealed to be reliable in treating cancers such as melanoma and breast cancer. Blushwood berry trees are stated to be exclusively seen in the jungles of Far North Queensland, Australia. However, tries to grow them in a greenhouse environment are being done.
EBC-46 Extract
Scientists have established a drug called EBC-46 from the compound extracts of blushwood berries which are said to have anticancer properties. Scientists state that the preparation of the drug is an intricate method and human trials are currently being performed. The anticancer results of this berry were first reported in 2004.
What does it do?
It is believed that the drug acts directly, denies the cancer cells off their oxygen supply, and also triggers the host immune response. Cancer cells exposed shriveling, shrinking, and cell death microscopically quickly after exposure to the drug.
EBC-46 activates an enzyme called protein kinase C; nevertheless, system included is still uncertain. Almost 75% of preclinical trials revealed appealing results with really little relapse in 1-year follow-up period and no negative effects. The drug was checked in quickly accessible tumors; nevertheless, its role in metastatic tumors is yet to be determined. Stage 1 medical human trials in cutaneous strong tumors such as melanoma squamous cell cancer (SCC), head and neck SCC, basal cell carcinoma, and Merkel cell carcinoma are underway. EBC-46 is a patented chemotherapeutic drug.
The seeds then goes through a drawing out procedure, The EBC-46 element is drawn out from seeds compounds, made into liquid, strong capsules or powder. Lastly it gets packaged in the UK’s best companies. [5]
How Blushwood Berries Can Destroy Cancer Cells Nearly Instantly
A research study conducted at QIMR Berghofer Medical Research Study Institute in Queensland, Australia has recently shed new light on what could end up being the next huge cancer treatment: the blushwood berry (Hylandia dockrillii). This naturally happening fruit consists of substances that started killing off cancer cells nearly instantly when studied in the laboratory.
Chemotherapy and radiation are harmful and included severe negative effects, frequently making the ill feel much more ill. The current research on this amazing berry could suggest brand-new, natural treatments for cancer on the horizon.
Blushwood Berries– Where they Come From
Blushwood berries are the fruit of the blushwood tree, which is known to grow in only one region of the world: the rain forests of Far North Queensland, Australia.
These tropical trees are not discovered anywhere else on the world, but grow in abundance near Australia’s northeastern pointer.
These particular trees need very specific niche conditions to prosper– conditions which can only be discovered in particular parts of Far North Queensland, Australia.
Considering their effectiveness as proven by the most current cancer research published in PLOS One, some are questioning if they could be grown in a greenhouse environment, so that individuals all over the world could gain from their cancer-killing residential or commercial properties.
Blushwood Berries– What sort of Cancer they Remove
The researchers at QIMR Berghofer Medical Research Institute, headed by Dr. Glen Boyle, utilized an experimental drug produced from the seeds of blushwood berries called EBC-46. They used this drug to deal with areas of cancer malignancy (the most fatal form of skin cancer) on canines, cats and horses.
The topics were diagnosed by veterinarians and offered a poor prognosis, most being thought about candidates for euthanasia prior to participating in the research study.
Astonishingly, these animals that had been on death’s door prior to the research study had their melanoma tumors disappear after treatment in the laboratory by Dr. Boyle and his team of researchers.
Growths were Gone within 48 Hours
When the EBC-46 was injected into the cancerous cells on the subjects, the growths reacted by turning a dark color, then falling off.
The derivative from the blushwood berry is thought to cut off oxygen supply to the cancer cells, allowing for the elimination of tumors without the need for surgery, chemotherapy or radiation therapy.
The scientists reported that the majority of the subjects’ growths– previously thought about a lost cause by vets– were gone within 2 days of being injected with EBC-46.
Under the microscope, the private cancer cells began shriveling up and dying within mere momentsof entering into contact with the EBC-46.
What the Future of Cancer Treatment Could Be?
The discovery of the effectiveness of EBC-46 is amazing news on the planet of cancer treatment.
D.r Boyle says the findings of the pre-clinical trials at QIMR Berghofer suggest the drug could be efficient in human patients.
” In many cases the single injection treatment caused the loss of viability of cancer cells within four hours, and eventually ruined the tumors.”.
Dr. Boyle states EBC-46 operate in part by activating a cellular response which successfully cuts off the blood supply to the growth. “In more than 70 percent of pre-clinical cases, the response and remedy was long-term and enduring, with extremely little relapse over a period of 12 months.”.
” We need to stress at this moment that EBC-46 will just be trialed in the short-term for tumors which can be accessed by direct injection or topical application,” Dr Boyle stated.
” There is no evidence to suggest EBC-46 would be effective versus metastatic cancers.”.
Further studies utilizing human participants might serve to prove the blushwood berry to be nature’s surprise cancer cure. [6]
Human trials for possible cancer remedy discovered in Australian jungle underway
Australian scientists are trialling the cancer-fighting homes in fruit from jungle trees in Far North Queensland.
EBC-46 is a particle found in the berries of the rainforest tree blushwood (fontainea picrosperma), which grows on the Atherton Tablelands.
” It’s a small molecule which works with the body to destroy cancer, instead of being a chemo-therapy method which can act versus the body,” Dr Victoria Gordon, CEO of Q-Biotics, informed TODAY.
She described the ingenious treatment worked by injecting the particle into the tumour site.
” We get full tumour damage in five to seven days, great healing … and no substantial side effects”.
The effects EBC-46 has actually been trialled with animals, consisting of Dr Gordon’s 18-year-old family pet canine who had an oral cancer malignancy.
” We injected the drug (EBC-46) and it simply seemed to liquefy (the tumour),” she said.
Early stages of human trials are underway, with 14 clients dealt with up until now.
” We’ve had no significant adverse effects and excellent lead to six tumour types”.
Dr Gordon emphasised there is still a “a long, hard road ahead” prior to a pharmaceutical can be developed from the drug. [7]
Promising ‘cancer-cure’ berries removed sale for fear of poisonous home remedy poisoning
‘ Most of the times the single injection treatment triggered the loss of viability of cancer cells within four hours, and eventually ruined the tumours,’ lead scientist Dr Glen Boyle informed the ABC.
Retailers of the native tree are scrambling to take the rain forest range off sale nevertheless, after fears that people could be poisoned attempting to create homemade cancer treatments.
‘ Our concern was people were simply going to grow it, get some fruit, crush it up and eat it,’ Roger Smith, supervisor of Yuruga Native Plant Nursery told the Cairns Post.
Scientist Steven Ogbourne of the University of Sunshine Coast says it’s not that easy, and a complex treatment is required to draw out the cancer-fighting substance.
Human trials are presently being prepared for the appealing drug. [8]
Conclusion
Fontainea picrosperma (Blushwood) are rare little shy spindly dioecious, damp enclosed jungle understorey trees requiring canopy defense. Some Fontaineas types survive in hasher conditions than the Blushwood. F.venosa can grow to 60 feet compared to 15 feet for Blushwood that grows at 2,300 feet to 3,600 ft. Blushwoods hate a cool temperature and need the nutrients, moisture and the defense of a damp rainforest. Alkaloids discovered in all Fontainea sap causes cancerous tumours to ablate, however there are only 200 of these native trees worldwide, so you will not legally be able to import these plants into the U.S.A. out of Australia. [9]
Referrals
- https://en.wikipedia.org/wiki/Fontainea_picrosperma
- https://apps.des.qld.gov.au/species-search/details/?id=17128
- https://www.herbal-organic.com/en/herb/197290
- https://apps.lucidcentral.org/rainforest/text/entities/fontainea_picrosperma.htm
- https://www.blushwoodforest.co.uk/
- https://www.seychellesweekly.com/2016/February%2015,%202016/beaute-sante1_blushwood_berries.html
- https://www.9news.com.au/health/cancer-fighting-berry-discovered/781a0d81-28f2-4f61-ba56-7895bc3e51ce
- https://www.thatslife.com.au/fears-of-cancer-cure-home-remedy-poisoning
- https://www.daleysfruit.com.au/forum/blushwood2/